http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111850078-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6225fbfe99cf6f6040f3258cf95852dd |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P35-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-14 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-75 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P35-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-14 |
| filingDate | 2020-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c86199894e60642dd44cd35d1558e3c8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_98af44976b41110d3f4e6c65a5191a2b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4bf61b8fa188145cf7df149839909d18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aab4652110701bf0bfd8565c87c3967f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ad43d827e98e8c12d16913ab7b2110fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_327adf45be2bb76f4ce78f308f962456 |
| publicationDate | 2020-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111850078-A |
| titleOfInvention | A kind of fermentation method of cephalosporin C |
| abstract | The invention discloses a fermentation method of cephalosporin C, comprising the following steps: step (1) taking C. acremonium for activation, taking a bacterial liquid with a mass volume concentration of 25%, and inoculating it into a seed culture medium according to an inoculation amount of 1% Medium culture, culture at pH 7.0 and 29°C for 90 hours to obtain first-class seed solution; step (2) take the first-class seed solution prepared in step (1), inoculate the seed medium according to 10% of the inoculation amount, and at pH Incubate at 6.5 and 28°C for 50 hours to obtain secondary seed liquid; step (3) take the secondary seed liquid prepared in step (2), inoculate it into the fermentation medium according to 20% of the inoculum for fermentation, and ferment for 30-140 h Add the whole material in the internal flow, stop the complete material after 140h of fermentation, and filter to obtain a fermentation broth; step (4) take the cephalosporin C liquid in step (3) for adsorption, drying, crystallization, washing, and drying to obtain cephalosporin C; adopt The above preparation method can improve the yield and titer of cephalosporin C. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114107237-A |
| priorityDate | 2020-07-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 51.