http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111849993-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2506-1353 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2500-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0654 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-077 |
| filingDate | 2020-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111849993-B |
| titleOfInvention | Gene inhibitor for promoting osteogenic differentiation of mesenchymal stem cells |
| abstract | The invention discloses a gene inhibitor for promoting osteogenic differentiation of mesenchymal stem cells. The gene inhibitor is shRNA of LINC 01877. The invention proves that the LINC01877 gene inhibitor can store ALP enzyme activity and calcification level of bone marrow mesenchymal stem cells, and mRNA level and protein level expression of osteogenic differentiation related genes RUNX2, ALP and OCN genes through ALP enzyme activity detection, alizarin red staining, real-time fluorescence quantification RCR and Western Blot, so that the LINC01877 gene inhibitor can be used for preparing osteogenic differentiation promoters of the bone marrow mesenchymal stem cells to promote osteogenic differentiation of the bone marrow mesenchymal stem cells. |
| priorityDate | 2020-03-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 180.