| abstract |
The invention discloses a method for synthesizing chlorogenic acid derivatives, which comprises the following steps: step 1, protection of chlorogenic acid alcohol hydroxyl group; step 2, protection of chlorogenic acid phenolic hydroxyl group; step 3, containing oxazole or pyrazole Synthesis of cyclic chlorogenic acid derivatives; Step 4, removal of hydroxyl protective group; the present invention can prepare high-efficiency antibacterial agents of chlorogenic acids, with remarkable antibacterial effect, and can also enhance the stability of unsaturated double bonds and improve green In vivo biological activity of ortho acids. |