| Predicate |
Object |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-21073
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-49
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P7-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-49 |
| filingDate |
2019-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2021-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2021-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-111840554-B |
| titleOfInvention |
Methods and medicaments for preventing or reducing bleeding conversion after administration of rtPA |
| abstract |
The present application relates to the use of a medicament to reduce the hemorrhagic transformation associated with treatment of cerebral infarction with rtPA by intervening peripheral blood immune cells. More specifically, the present application uses CCL inhibitors and integrin α 4 inhibitors that reduce peripheral blood immune cell migration to reduce bleeding episodes associated with rtPA dosing. |
| priorityDate |
2019-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |