| abstract |
The invention specifically relates to a vancomycin-modified black phosphorus quantum dot antibacterial agent, a preparation method and an application. The development of antibacterial drugs has the disadvantages of long cycle and high cost, and the development speed of bacterial resistance exceeds the development speed of drugs. In order to provide a drug with better antibacterial effect and reduce drug resistance, the present invention designs and uses vancomycin-modified black phosphorus quantum dots as an antibacterial active ingredient, and the vancomycin is bound to the surface of black phosphorus quantum dots through covalent bonds. It is confirmed by the research of the present invention that the antibacterial performance of the black phosphorus quantum dots modified by vancomycin is significantly improved, and is expected to become the first-line active ingredient of clinical antibacterial drugs, which has good development significance. |