http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111820185-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01K67-02 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01K67-02 |
filingDate | 2020-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111820185-B |
titleOfInvention | Propagation method of IFN-gamma gene defect homozygote mice and application thereof |
abstract | The invention discloses an IFN-gamma gene defect homozygote mouse propagation method and application thereof, wherein the propagation method comprises the steps of mating purchased IFN-gamma gene defect heterozygotes, mating homozygotes and heterozygotes in offspring, mating male homozygotes and female homozygotes in the offspring to obtain a large number of IFN-gamma gene defect homozygote mice, realizing the propagation of the IFN-gamma gene defect homozygote mice, and simultaneously, the obtained IFN-gamma gene defect homozygote mice have normal physique compared with the IFN-gamma gene defect homozygote mice directly purchased, can be better used for the establishment of cryptosporidium in vitro infection models, can cause rapid and chronic infection with extremely low dose, and have low mouse death rate in the process, and can meet the requirement of longer research period for cryptosporidium infection. And the FN-gamma gene defect homozygote mice obtained after propagation can be directly subjected to pure mating and postgeneration, so that mass propagation can be realized without complicated pure hybridization. |
priorityDate | 2020-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.