Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e0328dc1833863fe13dfa746048bec03 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1205 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0008 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y202-01002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-01011 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y401-01071 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y202-01001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y503-01027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y401-02043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01049 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y202-01006 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y102-01075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1022 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-88 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y101-01001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y207-01056 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-01 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-21 |
filingDate |
2020-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1376ae29394e24d59fb2c38be2db00c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54e8fc823ef983fe62d6fa08e260a4f9 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43797131df745e0d8a855e1a869804ab http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d97374e4650bd14825c52fd16f6b2a01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57fecee45ce8e4639df39057b49f8a72 |
publicationDate |
2020-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-111808791-A |
titleOfInvention |
Reconstructed methyl engineering bacterium for synergistic assimilation of methanol by ribulose monophosphate pathway and serine circulation pathway and application thereof |
abstract |
The invention provides a reconstructed methyl engineering bacterium for synergetically assimilating methanol by utilizing a ribulose monophosphate path and a serine circulating path and application thereof, belonging to the technical field of genetic engineering; the host bacteria of the reconstructed methyl engineering bacteria comprise methylotrophic bacteria naturally utilizing serine circulation to assimilate methanol; the exogenous genes introduced into the reconstructed methyl engineering bacteria comprise a coding gene of hexulose-6-phosphate synthase and a coding gene of hexulose-6-phosphate isomerase. The method takes methanol as a unique carbon source and energy source and methylotrophic bacteria which naturally utilizes a serine circulation path to assimilate the methanol as an initial host, introduces a gene hps for heterologous expression coding of the hexulose-6-phosphate synthase and a gene phi for heterologous expression coding of the hexulose-6-phosphate isomerase into the initial host, realizes the construction of a ribulose monophosphate path, and thus utilizes the ribulose monophosphate path and the serine circulation path to assimilate the methanol in a synergistic manner. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113151130-A |
priorityDate |
2020-07-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |