| abstract |
The invention discloses a preparation method of patchouli oil nano composite membrane for skin wound repair, which utilizes supercritical CO 2 The method comprises the steps of loading patchouli oil into mesoporous silicon nanoparticles to obtain high-drug-loading-capacity patchouli oil-mesoporous silicon nanoparticles, adding the patchouli oil-mesoporous silicon nanoparticles into a film matrix formed by mixing chitosan and polyvinyl alcohol, and carrying out high-speed magnetic stirring mixing, coating and freeze drying to obtain the patchouli oil nano composite film. In addition, the invention can also realize CO in the preparation process 2 And the recovery and cyclic utilization of the non-loaded patchouli oil are realized, so that the utilization rate is improved. |