http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111793239-B

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filingDate 2020-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-111793239-B
titleOfInvention A kind of preparation method of high-strength DNA hydrogel with macroporous structure
abstract The preparation method of a high-strength responsive DNA hydrogel with a macroporous structure of the present invention is that the polymer monomer and the DNA strand with a modified group at the 5' end are concentrated into the micro-liquid phase around the ice crystal under freezing conditions. , under the action of the initiator, the polymerization is carried out, that is, the DNA is grafted to the polymer chain through the polymerization reaction between the DNA modification group and the polymer monomer; due to the interaction between the DNA chains, the two or Multiple DNA strands are linked together, so DNA acts as a cross-linking unit to link the polymer strands into a polymer network, thereby forming a DNA hydrogel; while ice crystals act as a porogen, and after the reaction is completed, increasing the temperature makes The melting of ice crystals leaves interconnected macroporous structures; this process introduces the method of freeze polymerization into the preparation of DNA hydrogels. The obtained DNA hydrogels have good mechanical properties and fast response speed, which broadens the application field of DNA hydrogels.
priorityDate 2020-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 28.