http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111793012-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2601-14 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C327-22 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C327-22 |
filingDate | 2020-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111793012-B |
titleOfInvention | Novel sitagliptin intermediate and preparation method thereof |
abstract | The invention discloses a compound shown as a formula I for constructing a sitagliptin chiral key intermediate, which is stereospecifically converted into a compound shown as a formula II under the action of transaminase as a substrate, so that the compound is used for synthesizing sitagliptin. The substrate compound shown as the formula I has the advantages of good solubility, easiness in reaction, low cost, simplicity in operation, low environmental pollution, high chiral purity and the like. |
priorityDate | 2020-08-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 158.