http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111778327-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-178 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H20-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6883 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16H20-10 |
| filingDate | 2020-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111778327-B |
| titleOfInvention | miRNA for evaluating cadmium-induced liver injury resistance of plant phenolic substances and application thereof |
| abstract | The invention discloses miRNA for evaluating cadmium-induced liver injury resistance of plant phenolic substances and application thereof. According to research, the expression of miR-182-5p is reduced in a cadmium-induced liver injury HepG2 cell model; therefore, miR-182-5p can be used as a marker for diagnosing the condition that the cadmium induces the organism liver damage. Furthermore, the invention also finds that the expression of miR-182-5p can be remarkably up-regulated by interfering the cadmium-damaged HepG2 cells with plant phenolic substances. Therefore, the miR-182-5p can be used as a miRNA marker for evaluating the cadmium damage resistance of the plant phenolic substances. The invention expands the application direction of miR-182-5p and opens up a new way for further explaining the protection mechanism of heavy metal induced liver injury such as cadmium by plant phenols. |
| priorityDate | 2020-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 43.