| abstract |
The invention discloses a fluorescent nano-probe for liver-targeted zero crosstalk ratio detection of hydrogen sulfide, preparation and application thereof. The fluorescent nano-probe is based on 1-propynyl-2-(((dodecylthio) Thiocarbonyl)thio)-2-methylpropionate, styrene (St), polyethylene glycol methyl ether (PEGMA), tetraacetyl-a-D bromogalactose, sodium azide, A novel ratiometric fluorescent nanoprobe prepared from tetraphenylporphyrin, 2,4-dinitrobenzenesulfonyl chloride, 9,9-dioctylpolyfluorene-benzothiadiazole alternating copolymer and the like. The fluorescent nanoprobe can achieve high-selectivity and high-sensitivity ratiometric detection of hydrogen sulfide in pure aqueous solution, and can perform high-selectivity zero-crosstalk ratiometric detection of hydrogen sulfide. Liver-targeting function, and has the advantages of low cytotoxicity, excellent water dispersibility, large Stokes shift, etc., and has great application prospects in analytical chemistry, life science, and environmental science and other technical fields. |