http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111773219-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dd5cf244cffd43ac584c793af4641c22 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4439 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P13-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 |
filingDate | 2020-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1fd5f4bcd3c94f842bf9b78c4db31183 |
publicationDate | 2020-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111773219-A |
titleOfInvention | Application of PI3K inhibitor NVP-BYL719 in the preparation of novel coronavirus inhibitor |
abstract | The invention belongs to the field of pharmaceutical technology, and in particular relates to the application of a PI3K inhibitor NVP-BYL719 in the preparation of a novel coronavirus SARS-CoV-2 inhibitor. The results of in vitro cell tests show that the drug can inhibit the novel coronavirus SARS-CoV-2 2 Proliferate in cells. At the same time, the results of the challenge test in mice showed that the drug can effectively reduce the viral load in the lungs of infected mice, and has a significant therapeutic effect on infected mice. It can be used as a novel coronavirus SARS‑CoV‑2 inhibitor for the treatment of COVID‑19 pneumonia. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113082028-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113082028-A |
priorityDate | 2020-08-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.