abstract |
The invention discloses a composition, comprising: statin medicine and vitamin D as active ingredients, wherein the material ratio of the two is 1-80 mg of the statin composition and 1000-50000 units of vitamin D. The invention also discloses the preparation method and application of the solid self-microemulsion. The present invention can supplement the use of vitamin D in conjunction with statins, reduce and alleviate the related toxic and side effects of statins, and has important practical significance for promoting statins to reduce the level of low-density lipoprotein to the greatest extent and prevent the reconstruction of cardiovascular diseases. |