http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111748523-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2513-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-007 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0634 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K35-407 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K35-407 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-078 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-04 |
| filingDate | 2020-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-11-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111748523-B |
| titleOfInvention | A preparation method and application of immunoregulatory small extracellular vesicles |
| abstract | The present invention provides a method for preparing immunoregulatory small extracellular vesicles and its application. The preparation method includes the following steps: (a) culturing the primary isolated and purified animal cells in a culture system for a period of time to allow the accumulation of Immunomodulatory small extracellular vesicles at an effective concentration; (b) collecting the culture medium in step (a); (c) isolating the immunomodulatory small extracellular vesicles from the culture medium collected in step (b). The small extracellular vesicles provided by the invention have immunoregulatory activity, can activate macrophages, and transform to M1 phenotype, and provide a theoretical basis for the prevention or treatment of diseases caused or aggravated by immunosuppression. |
| priorityDate | 2020-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 266.