| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y601-01006
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C269-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C213-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-43595
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C09K11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C269-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y113-12007
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0069
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-93 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-435
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C09K11-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C269-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C217-46
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C271-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 |
| filingDate |
2020-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2021-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2021-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-111747869-B |
| titleOfInvention |
Genetically encoded formaldehyde reactive unnatural amino acid, preparation method and application thereof |
| abstract |
The present invention relates to a genetically encoded formaldehyde reactive unnatural amino acid. Specifically, the present invention discloses a genetically encoded formaldehyde-reactive unnatural amino acid PrAK, a preparation method and its application in the detection and imaging of formaldehyde. The formaldehyde-reactive unnatural amino acid PrAK provided by the present invention can be site-specifically introduced into biological macromolecules such as green fluorescent protein (EGFP) and firefly luciferase (fLuc) during protein translation to construct reactive biological macromolecular formaldehyde fluorescence Probes and bioluminescent probes that can effectively detect or image formaldehyde in biological samples. |
| priorityDate |
2020-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |