http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111732568-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D333-38 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D333-38 |
| filingDate | 2020-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111732568-B |
| titleOfInvention | A kind of synthetic method of 4-methoxycarbonyl-2-methylthiophene-3-sulfonyl chloride |
| abstract | The invention discloses a method for synthesizing 4-methoxycarbonyl-2-methylthiophene-3-sulfonyl chloride. The method for synthesizing comprises the following steps: S1, formula (I) 5-methyl-4-oxygen Substituted tetrahydrothiophene-3-methyl formate and methanesulfonyl chloride react under the action of a catalyst to obtain the intermediate of formula (II); S2, combine the intermediate of formula (II), anhydrous sodium sulfide and polar aprotic The solvent is mixed and reacted, and oxygen is introduced into the aromatization reaction to obtain the intermediate reaction solution of formula (III); S3, the intermediate reaction solution of formula (III) is sequentially subjected to chlorine oxidation and conventional post-treatment to obtain the target compound formula (IV) 4-methoxycarbonyl-2-methylthiophene-3-sulfonyl chloride; The method has short steps, simple operation, high yield, low cost and less waste water, and is more suitable for industrial production. |
| priorityDate | 2020-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 141.