http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111732542-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2531-0266 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2531-0244 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-2217 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D223-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D223-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B53-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-22 |
| filingDate | 2020-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-03-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111732542-B |
| titleOfInvention | Optically pure binaphthyl NN-dioxide ligand and preparation method thereof |
| abstract | The invention discloses a novel optical pure binaphthyl NN-dioxide ligand and a preparation method thereof, wherein (S) -3-bromobinaphthyl secondary amine and di-tert-butyl dicarbonate are subjected to condensation reaction to obtain a first intermediate, the first intermediate is subjected to benzyloxy carbonylation to obtain a second intermediate, the second intermediate is subjected to catalytic hydrogenation to obtain a third intermediate, the third intermediate and aromatic amine are subjected to condensation reaction to obtain a fourth intermediate, the fourth intermediate is subjected to acidolysis to obtain a fifth intermediate, the fifth intermediate and dibromo straight-chain alkane are subjected to disubstituted reaction to obtain a sixth intermediate, and finally the sixth intermediate is subjected to nitrogen oxidation to obtain the novel binaphthyl NN-dioxide ligand, wherein the structure of the novel optical pure binaphthyl NN-dioxide ligand is shown in the following formula (I). The invention creatively researches a preparation method of the novel binaphthyl NN-dioxide ligand, introduces an axial chiral binaphthyl skeleton into the NN-dioxide ligand and expands the diversity of the chiral skeleton in the NN-dioxide ligand. Effectively promotes the development of the chiral NN-dioxide ligand in the field of asymmetric catalysis. |
| priorityDate | 2020-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 78.