| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4e9883de94c040f08289415cd903bf87 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-333
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-39 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-8984 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K135-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-8984 |
| filingDate |
2020-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e23a202339b4a239748b62e717c63e4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a0e70b51d762a0f3db63f0d824f0d555
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0249cf5fb3554f72e4cc65725c84203f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7aa4347e322d9580d3af60a3dca34248
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6ceac2715d5351bfeb407e107874ad34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89c9506a0bca41b33885e97606f901a4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b7c283712aaad1e77527bc46cb4477f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c45b8e55023753d374ff07ee9507280 |
| publicationDate |
2020-10-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-111729037-A |
| titleOfInvention |
Application of dry dendrobium alcohol extract in preparing medicament for treating lipid metabolism disorder |
| abstract |
The invention belongs to the technical field of pharmacy, and relates to application of a dry dendrobium alcohol extract in preparation of a medicament for treating lipid metabolism disorder. Experimental results prove that the dry dendrobium alcohol extract prepared by the invention not only can obviously increase the mRNA expression levels of scavenger receptor class B I, proprotein convertase subtilisin kexin9, low-density lipoprotein receptor and lecithin cholesterol acyltransferase so as to effectively regulate the metabolism of cholesterol, but also can effectively inhibit the expression level of insulin-induced gene (INSIG2) so as to effectively regulate the synthesis of cholesterol, and also can obviously inhibit the expression level of Microsomal Triacylglycerol Transport Protein (MTTP) so as to effectively regulate the anabolism of Triglyceride (TG). Therefore, the dry dendrobium alcohol extract provided by the invention can be used for preparing a medicament for treating lipid metabolism disorder, and has a good development prospect in the aspect of treating the lipid metabolism disorder. |
| priorityDate |
2020-08-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |