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publicationDate 2020-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-111712522-A
titleOfInvention Anti-PD-1/anti-VEGF natural antibody structure-like heterodimeric bispecific antibody and preparation thereof
abstract Anti-PD-1/anti-VEGF natural antibody structure-like heterodimeric bispecific antibody and preparation thereof. Provided are an anti-PD-1/anti-VEGF bispecific antibody in the form of a highly stable heterodimer with natural IgG characteristics and no heavy and light chain mismatch and a preparation method thereof. The bispecific antibody can bind two target molecules at the same time and can be more effective in the treatment of complex diseases.
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