http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111710362-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B30-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B30-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-6869 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16B25-20 |
filingDate | 2020-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111710362-B |
titleOfInvention | Design method and application of capture probe based on next generation sequencing |
abstract | The invention provides a design method and application of a capture probe based on next generation sequencing. In order to ensure that the capture performance of all target areas is not influenced by the GC content of the areas, different probe design schemes are adopted in different GC content areas, the number of probe layers in different areas is dynamically adjusted according to the relation between the probe capture efficiency and the GC content of a probe coverage area, the number of probe layers is increased in an area with low GC content, and/or the number of probe layers is reduced in an area with high GC content; and the length of the overlapping part between the adjacent probes can be further adjusted, so that the probe capture uniformity of the whole target area is improved. |
priorityDate | 2020-08-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 19.