Predicate |
Object |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2710-10343 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-86 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-111 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-66 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-861 |
filingDate |
2020-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2022-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate |
2022-12-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
CN-111705081-B |
titleOfInvention |
Construction and application of shRNA adenovirus carrying human RhoGDI3 gene |
abstract |
The invention discloses the construction and application of a shRNA adenovirus carrying human RhoGDI3 gene, belonging to the technical field of biomedicine. The adenovirus contains shRNA that inhibits the expression of human RhoGDI3 gene, and the sequences of the shRNA are shown in SEQ ID NO.1 and SEQ ID NO.2. The adenovirus of the invention can knock out the RhoGDI3 gene in vivo to achieve the effect of inhibiting the hyperplasia of vascular intima, and is used for preparing medicine for treating vascular diseases. |
priorityDate |
2020-06-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |