| abstract |
The invention relates to a polysaccharide/polydopamine hybrid hydrogel, a preparation method and application thereof. The preparation method comprises: preparing a polydopamine solution by oxidative self-polymerization under certain conditions, and uniformly dispersing the polysaccharide and polydopamine After heating to 80 °C and then cooling to form a hydrogel, co-culture with a variety of fibroblasts shows good biocompatibility, and polydopamine can regulate the microstructure, mechanical properties, and swelling properties of the polysaccharide hydrogel. And ion response behavior, etc., the hybrid hydrogel can be used as a tissue engineering material for fibroblast culture in vitro, providing a way of in vivo application of polysaccharide-based hydrogel in tissue engineering. |