| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_653c418e41edbb4e1ce8bc5e53e70cec |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2420-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2430-40 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-047
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C23C22-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-3804
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-06 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C23C22-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-50
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-06 |
| filingDate |
2020-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5df7ec48c3450e6923a6d3c7b31b5e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de765b55a494c6cbe8cc8ad91e025a67
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d27cf7dd7da8364518d14a84f0aecf45 |
| publicationDate |
2020-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-111701076-A |
| titleOfInvention |
Exosome-loaded metal-based implant material and preparation method and application thereof |
| abstract |
The present invention relates to an exosome-loaded metal-based implant material and a preparation method and application thereof. Exosomes including metal matrix, calcium phosphate conversion membrane, surface-modified PEGylated phospholipid, metal matrix covered with calcium phosphate conversion membrane, calcium phosphate conversion membrane and surface-modified PEGylated phospholipid exosomes The hydrophilic end of the PEGylated phospholipid forms a Ca 2+ ‑O‑PEG complex with the calcium phosphate conversion membrane, and the hydrophobic end of the PEGylated phospholipid binds to the phospholipid bimolecular structure layer of the exosome. Provide micro-nano scale and rough surface to improve the binding specific surface area of exosomes. Increase the binding capacity of exosomes. Improves surface bioactivity and bone regeneration. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113440653-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115501387-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115501387-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115518194-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113999399-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113999399-A |
| priorityDate |
2020-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |