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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-69
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filingDate 2020-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2021-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2021-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-111700861-B
titleOfInvention A kind of gelsolin inclusion and nanometer method and suspension
abstract The invention belongs to the field of nanoparticle preparation in biochemical technology, and particularly relates to a gelsolin encapsulation and nanometerization method and suspension. The implementation scheme is: in parts by mass, under normal temperature conditions, add gelsolin and hydroxypropyl-β-cyclodextrin into a mortar at a ratio of 1:10, add a small amount of pure water and grind for 4 hours, and then mix It was filtered and freeze-dried to give the cyclodextrin/gelsolin inclusion complex. The inclusions are nanosized to obtain a nanosuspension of the gelsolin-cyclodextrin inclusions. The method of the invention does not use organic solvents and toxic cross-linking agents, and has the advantages of simple operation, good entrapment effect, good reproducibility, safety and reliability.
priorityDate 2020-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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