http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111699023-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_28bdd00e6c180acf9ad99fa2004da77e |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4422 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4433 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-04 |
| filingDate | 2018-12-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_404962eee030b66f17fd9327882991f0 |
| publicationDate | 2020-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111699023-A |
| titleOfInvention | Mitochondrial targeting, MPTP regulation, and reduction of mitochondrial reactive species and/or mitochondrial reactive lipid species |
| abstract | Provided herein are compounds that react with reactive lipid species to form innocuous or active products. Also provided are methods of reducing reactive lipid species. Also provided are methods of treating mitochondria in patients with mitochondrial dysfunction. In other embodiments, a compound is provided that reacts with an activator present in mitochondria to form an active product that inhibits or enhances the opening of the mitochondrial permeability transition pore (MPTP). In additional embodiments, methods of inhibiting or enhancing the opening of MPTP are provided. Also provided are non-polar compounds capable of crossing the blood brain barrier (BBB) into the central nervous system (CNS). |
| priorityDate | 2017-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 2214.