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filingDate 2019-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-07-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-111693615-B
titleOfInvention Analytical method for simultaneous determination of niacin, vitamins B1, B6 and pantothenic acid
abstract The invention provides a liquid chromatography analysis method for simultaneously and efficiently determining niacin, vitamin B 1 , vitamin B 6 and pantothenic acid in complex components. The method uses 0.1M potassium dihydrogen phosphate and 0.01M dipotassium hydrogen phosphate mixed solution-acetonitrile as the mobile phase for gradient elution, which can avoid the interference of other components, and can accurately and sensitively detect niacin and vitamins within 28 minutes. Contents of B1, vitamin B6 and pantothenic acid. The method has strong specificity, high precision, good stability, high accuracy, simple operation, and cheap and easy-to-obtain reagents and consumables. It is suitable for medicines and foods in tablet, powder, capsule and other dosage forms containing niacin, vitamin B 1 , vitamin B 6 and pantothenic acid. The quality control of the four components can effectively save testing cost and time.
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