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filingDate 2019-03-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cda45f7816781e9b392b90a8f2e56a0c
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publicationDate 2020-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-111689923-A
titleOfInvention A novel skeleton cyclolipopeptide compound with the activity of reversing tumor multidrug resistance, its preparation method and use
abstract The present invention relates to the neem family woody plant hong kong A new skeleton cyclolipopeptide compound that can reverse the drug resistance activity of tumor cells is isolated from wood. The compound has a novel structure and can significantly improve the proliferation inhibitory activity of chemotherapeutic drugs on multidrug-resistant tumor cells. The present invention relates to an extraction, separation and preparation method of the compound, and also relates to its use for preparing a drug for treating certain multidrug-resistant tumors.
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