http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111686399-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-245 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A62D2101-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A62D3-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B09C1-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B09C1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-689 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-025 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A62D101-43 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B09C1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-689 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B09C1-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A62D3-02 |
| filingDate | 2020-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-05-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111686399-B |
| titleOfInvention | Reagent for inhibiting expression of antibiotic resistance genes of bacteria under metal induction and preparation method and application thereof |
| abstract | The invention discloses a reagent for inhibiting the expression of antibiotic resistance genes of bacteria under the induction of metal, a preparation method and application thereof. The method comprises the following steps: adding montmorillonite into water, centrifuging to obtain precipitate, adding the precipitate into water again, repeatedly centrifuging until the supernatant is clear, oven drying, sieving, adding into solvent, and mixing to obtain the agent for inhibiting the expression of antibiotic resistance gene under metal induction. The reagent regulates Cd by utilizing Mt 2+ Inducing the expression pattern and metabolism of bacterial antibiotic resistance genes against low-dose antibiotic stress, thereby inhibiting E.coli Expression of antibiotic resistance genes. The results of minimum inhibitory concentration and fluorescent quantitative PCR also show that Mt can weaken Cd 2+ The expression of bacterial antibiotic resistance is induced. Therefore, Mt can be used as an environmental material to relieve the expression of bacterial antibiotic resistance genes under heavy metal stress, and has important significance for controlling ARGs pollution caused by the expression. |
| priorityDate | 2020-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 31.