| abstract |
The invention relates to the technical field of medicine, in particular to a new application of Prunella vulgaris flavonoids. The invention discloses new applications of Prunella flavonoids, in particular to the preparation of drugs for inhibiting bacterial quorum sensing system, the preparation of drugs for inhibiting bacterial pyocyanin, the application of drugs for inhibiting bacterial elastase secretion, and the application in the preparation of drugs for inhibiting bacterial elastase secretion. Application in the preparation of medicines for inhibiting bacterial biofilm formation. The Prunella vulgaris of the present invention can achieve the bacterial virulence factor by inhibiting the quorum sensing system, without inhibiting the growth of the strain, and is not easy to produce the effect of bacterial drug resistance, and exerts the effect of inhibiting Pseudomonas aeruginosa. In addition, Prunella vulgaris flavonoids are natural substances with very low toxicity and side effects. Prunella vulgaris flavonoids can be used alone or as an auxiliary therapeutic agent for antibiotics to prevent and treat bacterial infections. |