http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111686124-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-141 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1136 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P29-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7105 |
| filingDate | 2020-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-07-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111686124-B |
| titleOfInvention | Application of miR-486-3p in preparation of product for treating neuroinflammation caused by SAH (neuroinflammation) |
| abstract | The invention discloses an application of miR-486-3p in preparation of a product for treating neuroinflammation caused by SAH, and provides an application of miR-486-3p related biomaterial in preparation of a product (a1) or (a2) as follows: (a1) preparing a product for treating subarachnoid hemorrhage; (a2) preparing a product for inhibiting neuroinflammation caused by subarachnoid hemorrhage; the related biological material of the miR-486-3p is miR-486-3p, or an exosome loaded with miR-486-3p, or a substance capable of promoting the expression of miR-486-3 p. Experiments prove that miR-486-3p loaded on exosome modified by RVG fused to membrane glycoprotein Lamp2b can more effectively transfer miRNA to brain. miR-486-3p exerts an anti-inflammatory effect by inhibiting the expression of Sirtuin2(Sirt 2). |
| priorityDate | 2020-05-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 145.