http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111686077-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G65-33327 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6907 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1075 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-519 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G65-333 |
filingDate | 2020-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2022-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2022-08-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111686077-B |
titleOfInvention | Aminoevodiamine polymer micelle and its preparation method and application |
abstract | The invention discloses amino evodiamine polymer micelles and a preparation method and application thereof. A 2-nitroevodiamine derivative is prepared from a carboline compound and N-methyl-7-nitrosatinic anhydride. The aminoevodiamine derivative is reduced to obtain aminoevodiamine derivative, and the polymer is reacted with aminoevodiamine to prepare aminoevodiamine polymer conjugate; then the aminoevodiamine polymer conjugate is self-assembled to obtain aminoevodiamine polymer conjugate To improve the water solubility and bioavailability of drugs, combine drugs with nanotechnology, and develop nano-drug loading systems for drug delivery. Nano-drugs can be passively targeted and enriched in tumor tissues through the EPR effect. |
priorityDate | 2020-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 52.