http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111676259-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-305 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-207 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-207 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-10 |
| filingDate | 2020-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-11-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111676259-B |
| titleOfInvention | A kind of preparation method of sugar nucleotide and derivative thereof |
| abstract | The invention discloses a preparation method of sugar nucleotides and derivatives thereof. The present invention uses monosaccharide and its derivatives as raw materials, utilizes biological enzymes to catalyze the synthesis of sugar nucleotides and their derivatives, the unreacted raw materials and impurities are selectively precipitated by barium ions, and the precipitates are removed by centrifugation, and finally high-purity compounds are obtained. Sugar nucleotides and their derivatives. The biological enzyme disclosed in the present invention is derived from prokaryotes, and has the advantages of high protein expression, wide substrate adaptability and high catalytic efficiency, and the catalytic synthesis of the biological enzyme has the advantages of high efficiency, high regioselectivity and the like. The invention also optimizes the reaction concentration of biological enzymes, and efficiently synthesizes expensive sugar nucleotides and derivatives from cheap and easily available monosaccharides and derivatives thereof. The invention also uses the ion precipitation method to purify the product, the purification step is simple and easy to scale up, and can reduce the cost and improve the product yield. |
| priorityDate | 2020-07-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 431.