http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111671971-B

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filingDate 2020-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2022-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-111671971-B
titleOfInvention Polypeptide single-layer film with 6% primary amino group exposure and preparation method and application thereof
abstract The invention provides a polypeptide single-layer film with 6% of primary amino group exposure, and a preparation method and application thereof. The polypeptide has a molecular weight of (1.48 +/-0.2) x 10 5 The single-layer film is 14.6 +/-0.1 nm in thickness, the primary amino group exposure on the film surface is 6 +/-0.3%, and the Zeta potential of the polypeptide single-layer film is-4.48 +/-0.1 mV; the contact angle of the film was 45 ± 1 °. The polypeptide single-layer film has good stability, the exposure of primary amino groups on the surface of the film is accurately controlled to be 6.0 +/-0.3%, the polypeptide single-layer film can be applied to a coating material on the surface of an oral implant, can carry antibiotics and antibacterial drugs and stably release the antibiotics and the polypeptide single-layer film has the advantages of small toxic and side effects on the whole body, strong antibacterial property and the like, is uniformly and tightly combined with a pure titanium material and is not easy to separate and fall off.
priorityDate 2020-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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