http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111662891-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2800-22 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-1051 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-58 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-465 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-70 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-58 |
| filingDate | 2020-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111662891-B |
| titleOfInvention | Piericidin glycosyltransferase sbmGT1 and application thereof |
| abstract | The invention provides a piericidin glycosyltransferase sbmGT 1; also provides the amino acid sequence and the nucleotide sequence of the glycosyltransferase; and provides a cloning and expression method of the saccharification transferase. The glycosyltransferase sbmGT1 is responsible for the glycosylation modification step of the piericidin in an organism and has the capacity of directionally improving the yield of the glycosylated piericidin; on one hand, the method fills up the technical blank of glycosylation modification after biosynthesis of the piericins compounds in the prior art, and on the other hand, the method greatly enhances the inhibition activity of the piericins compounds on tumor cell proliferation; therefore, the method has important economic value and has more important social significance. Moreover, when the nucleotide sequence of glycosyltransferase sbmGT1 is the preferable nucleotide sequence, the yield of compound 10-glucopericidin A with the best activity of inhibiting tumor cell strain proliferation is obviously improved, and the method has important social significance and can generate great economic benefit. |
| priorityDate | 2020-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 265.