http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111662477-B
Outgoing Links
Predicate | Object |
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classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2301-18 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J7-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J7-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-558 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J7-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J7-123 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-558 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J7-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J7-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J7-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J7-12 |
filingDate | 2020-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-02-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111662477-B |
titleOfInvention | Modification method of nitrocellulose membrane applied to immunochromatography |
abstract | The invention discloses a method for modifying a nitrocellulose membrane applied to immunochromatography, which comprises the following steps: treating the nitrocellulose membrane under a low-power plasma condition for a short time to activate the surface of the nitrocellulose; introducing methacrylic acid MAA into a vacuum chamber in a gaseous state, and initiating a grafting reaction between the gaseous MAA and the surface of the nitrocellulose membrane by using a plasma to obtain a plasma modified nitrocellulose membrane with a surface rich in carboxyl; spraying 1-cyclohexyl-2-morpholine ethyl carbodiimide (CMC) on the surface of the modified membrane to react with the CMC to generate a nitrocellulose membrane with active groups which can be used for protein fixation, and drying and storing the obtained modified membrane in vacuum, wherein the nitrocellulose membrane can be used for preparing immunochromatography test paper. The modification method has the advantages of simple operation, high treatment efficiency and the like, the obtained modified membrane has the characteristics of strong hydrophilicity, high protein loading capacity and stable protein fixation, and the modified membrane can improve the performance of a reagent in an immunochromatography project, avoid the tailing phenomenon in test strip detection, reduce the dosage of an antibody and the like. |
priorityDate | 2020-06-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 41.