http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111662315-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2231-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J2531-822 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F5-027 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-2295 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B01J31-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-69 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-07 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-00 |
| filingDate | 2020-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111662315-B |
| titleOfInvention | 3-substituted oxazole fused cage-like dodecaborane compound and preparation method and application thereof |
| abstract | The invention discloses a 3-substituted oxazole fused cage dodecaborane compound and a preparation method and application thereof. The structure of the 3-substituted oxazole fused cage-shaped dodecaborane compound is shown as a formula (I), and R is 1 Is menthyl or camphoroyl; said R 2 Is H, C 6‑20 Aryl radical, C 1‑15 Alkyl, -C (O) O-C 1‑5 Alkyl or-C (O) O-C 6‑20 Aryl radical, said C 6‑20 Aryl is optionally substituted by 1,2 or 3H, F, Cl, Br, I, OH, NH 2 、NO 2 、CN、C 1‑5 Alkyl radical, C 1‑5 Alkoxy, -O-C (O) -C 1‑5 Alkyl, -C (O) -NH-C 1‑5 Alkyl, -NH-C (O) -C 1‑5 Alkyl, -C (O) O-C 1‑5 Alkyl radical, C 6‑20 Aryl or 5-12 membered heteroaryl; a is described + Is a metal cation, a quaternary ammonium cation or a phosphonium cation. The preparation method utilizes menthyl and camphor as guide groups to selectively activate a 3-bit B-H bond to prepare the compound shown in the formula (I); high stereoselectivity and good yield, and increases the chance of finding novel antibacterial candidate drugs. The compound of formula (I) provided by the invention has high-efficiency and broad-spectrum antibacterial effect. |
| priorityDate | 2020-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 150.