| abstract |
The invention relates to a small molecule compound with 2H-indazole structure and its synthesis and application. Specifically, the present invention discloses the compound of formula (I), its enantiomers, diastereomers, racemates or mixtures thereof, or pharmaceutically acceptable salts, hydrates and Solvate and its preparation method and use in preparing kRAS small molecule inhibitor, or medicine for preventing and/or treating kRAS-related diseases, especially tumor diseases, in the formula, the definition of each substituent is as in the description and claims described in the book. |