http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111658651-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-5377 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P27-02 |
| filingDate | 2020-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-08-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111658651-B |
| titleOfInvention | Application of CQMU151 in preparing medicament for treating Th17 cell-mediated autoimmune disease |
| abstract | The invention relates to application of 1H-benzo [ d ] imidazole-2-yl) methyl) -3- (morpholinosulfonyl) benzamide in preparation of a medicament for treating Th17 cell-mediated autoimmune disease. The invention obtains the compound by screening from the Chembridge compound library, and experiments show that: the compound has the function of inhibiting the differentiation of Th17 cells in vitro; can inhibit the differentiation of Th17 cells and the generation of IL-17 in vivo, and relieve the clinical symptoms of autoimmune diseases such as Th17 cell-mediated Experimental Autoimmune Uveitis (EAU), Experimental Autoimmune Encephalomyelitis (EAE), type 1 diabetes and the like, and has good application prospect. |
| priorityDate | 2020-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 36.