http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111657267-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A01N1-0221 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N1-02 |
| filingDate | 2020-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2021-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2021-02-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111657267-B |
| titleOfInvention | Ice-free crystal frozen preservation solution and freezing method for preservation of cartilage, tendon and meniscus |
| abstract | The invention discloses an ice crystal-free cryopreservation liquid and a freezing method for cartilage, tendon and meniscus preservation, wherein the cryopreservation liquid comprises 1.0-6.0mol/L of ethylene glycol, 1.0-7.0mol/L of propylene glycol, 0.1-2.5mol/L, Caspase inhibitor Z-VAD-FMK 10-50 mu mol/L, 2-10mg/L of matrix metalloproteinase inhibitor GM6001 and a component X. The preservation solution disclosed by the invention can effectively improve the number of living cells and the cell survival rate in the tissues after the cartilage, tendon and meniscus tissues are frozen and preserved, and more importantly, can prevent the ice crystals from regrowing during freezing recovery and storage, and prevent devitrification. The novel ice crystal-free freezing protection solution can be used for preserving cartilage, tendon and meniscus for a longer time and can be preserved permanently at the temperature of less than-130 ℃. |
| priorityDate | 2020-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 50.