| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1e02b18dfce047ff0f2394874a7e9aeb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5387e4878022155907b403fb8d47b509
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aa71c8a01ee13aef0e154cea7a1252a9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_bd8d77c5af013ff7055cd52997d5b677 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70532 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6872
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N21-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57423
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57492 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N21-31
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 |
| filingDate |
2020-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee6c50565936b5ef7d43ca0957cad40f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1803e7ecfcd1b91ca94fb6fcb2cea520
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_49c74ae0d0d25ea2fc37762f672e2d41
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4ac3a187e32572ff35adc19b0159b31b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_22103d9fba830c43ab7ac39a57129432
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a7cdeaa5d71bf760d1d8d3f1be9bab89
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_84df2c1b7820d8e940d4aeeb28c83681
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7931b13d1e2f7cba761034d605b51926
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e327c916505eae98bb968ec0e54cf3bf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e2c1b1a8455ed03f4d141a381a526468
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c7629c1e1b9b059be36fec9035fb48fd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_80e2e1936872dd7dcaa47124746d5674 |
| publicationDate |
2020-09-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-111650382-A |
| titleOfInvention |
A kind of targeting peptide-mediated gold nanoparticle biosensor, preparation method and application thereof |
| abstract |
The invention relates to the technical field of medicine, in particular to a targeting peptide-mediated gold nanoparticle biosensor and a preparation method and application thereof. The targeting peptide-mediated gold nanoparticle biosensor of the present invention is composed of a gold nanoparticle modified with a polypeptide containing an aromatic residue at the N-terminus of the PD-L1 protein on the surface of exosomes. Volume resonance (SPR) characteristics can be used for colorimetric contrast detection analysis. The targeting peptide-mediated gold nanoparticle biosensor of the present invention can be used to analyze the PD-L1 level on the surface of exosome samples, and the operation is simple, and it is the beneficiary group of people who pass the PD-1/PD-L1 immune checkpoint therapy. Screening provides reference. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021076865-A1 |
| priorityDate |
2020-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |