| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-70596
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57419
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6872
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57484
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57446 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-10 |
| filingDate |
2020-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2022-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2022-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-111647046-B |
| titleOfInvention |
CD133 antagonistic polypeptide, derivative and application thereof |
| abstract |
The invention relates to a CD133 antagonist polypeptide, a derivative and an application thereof, and particularly discloses a CD133 antagonist polypeptide: the amino acid residue sequence of the CD133 antagonist polypeptide HL12-CP2 is shown as SEQ ID No. 1. The binding peptide and the derivatives thereof can bind to CD133 in vitro, block a downstream signal path thereof through the binding with the CD133 so as to inhibit the proliferation of colorectal cancer cells, promote the apoptosis of the colorectal cancer cells, provide effective small molecule treatment medicines for colorectal cancer and the like, and can be widely applied in the fields of medicine and biology. |
| priorityDate |
2020-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |