| abstract |
The invention discloses a manganese-containing micro-precipitation liposome for immunotherapy and a preparation method thereof. The liposome consists of a manganese ion-containing micro-precipitation core and a phospholipid bilayer shell, and can be prepared by combining an emulsion mixing method and a film dispersion method. The liposome has a spherical structure of 20-200nm, has a certain amount of positive charges on the surface, and can be degraded in a certain acidic environment. The liposome can stimulate innate immune system and/or adaptive immunity or be used as an immunologic adjuvant for treating related diseases such as antiviral, antibacterial, antitumor and autoimmune diseases. |