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filingDate 2018-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2020-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-111629691-A
titleOfInvention Apparatus and method for creating a fluidic containment field for administering therapeutic agents to nerves
abstract Severed nerves can be surgically reconnected and severed axons fused via sequential administration of the solution. The solution may include a prefill solution comprising methylene blue-containing Ca2 +-free salt solution, a fusion solution comprising about 50% (w/w) PEG, and a sealing solution comprising a Ca2 + -containing salt solution. The PEG fusion solution can be applied to a neurotherapy device configured to isolate a damaged segment of a nerve. The device may include a containment chamber for creating a fluid containment field around the anastomosis. The device may have slits, slots and/or holes in opposing end walls of the device designed to receive nerves. The apparatus may have an open bath configuration, or may include separable lower and upper bodies to form a closed bath configuration. The device may include one or more fluid ports in fluid communication with the containment chamber for introduction and/or removal of fluid.
priorityDate 2017-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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