http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111621052-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_39a580217230a7f3ba4f0a609b2437d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_be2c55a9de09e08e3404c0a5a1ae4dc7 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2389-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J2343-02 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0655 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08J7-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-077 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L89-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J7-12 |
| filingDate | 2020-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6ba0435cbaf2b26019f0349884457a6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df07569a9a3fd708be2b6892f9b9c4d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6b65e719ecfb58bd41faac12eb88de60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4f7c59b40e66983600de8fe5b1dc3586 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_783b0ec78c80830207a809b4f3930cb3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7855a2a236ffb4aad0edb160c7fa2686 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_882ce6a8046d7decbe9d847efe58a562 |
| publicationDate | 2020-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111621052-A |
| titleOfInvention | Gel matrix based on dopamine-grafted zwitterionic-polymerized phosphorylcholine-modified type I collagen and preparation method thereof |
| abstract | The invention relates to a gel matrix based on dopamine grafted zwitterionic polymerized phosphorylcholine modified type I collagen and a preparation method thereof, belonging to the technical field of biological materials; the novel gel matrix comprises modified zwitterionic polymeric phosphorylcholine and modified type I collagen. Firstly synthesizing dopamine-grafted modified zwitterionic polymeric phosphorylcholine through amidation reaction, and then connecting the zwitterionic polymeric phosphorylcholine to the surface of the I-type collagen matrix through the adhesiveness during dopamine oxidative polymerization, thereby obtaining the novel gel matrix based on the dopamine-grafted zwitterionic polymeric phosphorylcholine-modified type I collagen. The novel gel matrix prepared by the method has excellent lubricating property, anti-inflammatory factor property and good biocompatibility, can be well combined to the surface of damaged cartilage, overcomes the defects of insufficient mechanical property and poor anti-inflammatory factor property of single type I collagen, is simple and convenient in preparation method, easy in raw material synthesis, good in feasibility and practicability, and can be widely applied to articular cartilage repair. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113662189-A |
| priorityDate | 2020-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 82.