| abstract |
The invention discloses a separation and purification method and application of two new compounds of plantain roots. The chemical names of the new compounds are 4-Phenyl-benzo[de]isoquinoline-1, 3-dione(1), 4-(4-Hy droxy- The structural formula of phenyl)‑benzo[de]isoquinoline‑1,3‑dione(2) is: The present invention adopts high-resolution mass spectrometry HR-ESI-MS, 1 H NMR, 13 C NMR, two-dimensional HMBC and HMQC nuclear magnetic spectrum to identify the structures of the two new compounds, and deduce the molecular formulas and molecular structures of the two new compounds. In vitro cell activity studies have shown that the two new compounds isolated from plantain roots have good inhibitory activity on human liver cancer cells, human lung cancer cells and human breast cancer cells, and the compounds can be developed and prepared as anti-tumor drugs. drug. |