| abstract |
The invention belongs to the field of medicine, and relates to a compound 3,7,11-cembretriene-2,6-diol and a preparation method and application thereof. ‑2,6‑Diol has obvious effects on preventing and treating neurodegenerative diseases. First, it has obvious protective effect on the damage of SH‑SY5Y cells by oxygen and glucose deprivation; obvious protective effect. Pharmacological tests have shown that these compounds can effectively inhibit the neuronal damage induced by oxygen-glucose deprivation and glutamate, and have the potential to be further developed into drugs for the prevention and/or treatment of neurodegenerative diseases such as stroke. |