http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111603468-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4375 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-485 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1623 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1652 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0004 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4375 |
filingDate | 2020-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2021-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2021-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-111603468-B |
titleOfInvention | A kind of berberine composition and its preparation method and application |
abstract | The present invention is applicable to the technical field of medicine, and provides a berberine composition, a preparation method and application thereof. The berberine composition comprises berberine, hydrophilic auxiliary materials, microcrystalline cellulose, lactose, and a binder. , disintegrant, glidant. Wherein, the hydrophilic auxiliary material is mannitol and/or sorbitol; the binder is polyvinylpyrrolidone and/or hydroxypropyl methylcellulose; the disintegrant is crospovidone or croscarmellose sodium ; Glidants are talc and/or silicon dioxide. In the present invention, the berberine is dispersed by using a hydrophilic auxiliary material, and under the action of a small amount of water-insoluble auxiliary materials such as microcrystalline cellulose, it is beneficial to granulation and disintegration of the particles, so that the medicine is completely disintegrated in a short time. And the rapid dissolution will not bring about the problem of the uniformity of the concentration of the sitz bath medicinal solution, and does not require stirring, which improves the convenience of use. |
priorityDate | 2020-06-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 47.