http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-111592596-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2410-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-622 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-33 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-1203 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-12 |
| filingDate | 2020-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2022-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2022-02-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-111592596-B |
| titleOfInvention | Microcystin broad-spectrum recognition single-chain antibody and application thereof in epitope prediction |
| abstract | The invention relates to a Microcystin (MC) broad-spectrum recognition single-chain antibody, which is constructed by taking a mouse hybridoma cell strain with a preservation number of CCTCC No. C2019 and resisting MC-LR as a template; the single-chain antibody has similar recognition capability to three arginine microcystins 4 (MC-LR, MC-YR and MC-RR), has higher cross reaction rate to non-arginine microcystins 4 MC-LA, and has high broad spectrum; the single-chain antibody is used for epitope prediction of MC-LR, and shows that the carbonyl and phenyl of Adda amino acid at position 5 and the guanidyl of arginine at position 4 of MC-LR are key epitopes of MC-LR, and the epitope prediction result is consistent with the result of antibody cross-reactivity. The research result provides beneficial information for MC family hapten design, antibody directed modification and understanding of antibody recognition capability. |
| priorityDate | 2020-06-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 186.