| abstract |
The invention provides a pharmaceutical composition for treating refractory hypertension, which is composed of amlodipine, chlorthalidone and an aldosterone receptor antagonist. The pharmaceutical composition provided by the present invention provides an effective antihypertensive drug for refractory hypertension patients, especially low renin/aldosterone normal or low renin/aldosterone elevated type refractory hypertension patients. The pharmaceutical composition provided by the invention can also strengthen the protective effect on the target organs of patients with refractory hypertension, and reduce the risk of cerebrovascular events. |